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An in vivo study included a rat model, found that NAC effectively prevented pulmonary edema and acute kidney injury during sepsis, particularly under mechanical ventilation stress, by preserving mitochondrial function and capillary integrity (Campos et al., 2012)

The body is relatively efficient at converting naturally occurring sources of folate through the small intestine via an enzyme that firstly removes the tail of the glutamate molecule for it to be absorbed, and once absorbed the folate molecules are then transformed into L-5-methyltetrahydrofolate (L-5MTHF)

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