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References The Lancet Once-weekly semaglutide versus placebo in patients with alcohol use disorder and comorbid obesity: a randomised, double-blind, placebo-controlled trial PubMed / Psychoneuroendocrinology Egecioglu et al., The glucagon-like peptide 1 analogue Exendin-4 attenuates alcohol mediated behaviors in rodents (2013) FDA FDA Qualifies Drug Development Tool to Facilitate Clinical Trial Research for Alcohol Use Disorder (February 14, 2025) American Journal of Psychiatry Targeted Oral Naltrexone for Mild to Moderate Alcohol Use Disorder Among Sexual and Gender Minority Men: A Randomized Trial Drug and Device Law Blog FDA Final Guidance, Communications From Firms to Health Care Providers Regarding Scientific Information on Unapproved Uses (January 6, 2025) First Word Pharma STEP clinical trial program: semaglutide 2.4 mg weight loss outcomes (STEP 1: 14.9% mean weight loss from baseline) FDA Psychedelic Drugs: Considerations for Clinical Investigations (Draft Guidance) Moe Alsumidaie is Chief Editor of The Clinical Trial Vanguard