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According to the UK Summary of Product Characteristics (SmPC), the most frequently reported adverse reactions include: Nausea (very common, particularly at higher doses) Diarrhoea and vomiting (common to very common) Decreased appetite (very common) Constipation (common) Abdominal pain or discomfort (common) Dyspepsia (indigestion) (common) These gastrointestinal effects are typically most pronounced when initiating treatment or increasing the dose, and often diminish over time as the body adjusts to the medication

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Seeing reductions across every disorder, I was like, Is this real? because there is nothing like it, says clinical epidemiologist Ziyad Al-Aly, lead author of the study and chief of research and development at the U.S