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Multiple studies have shown improvements in markers of metabolic dysfunction-associated steatotic liver disease (MASLD, formerly NAFLD) and metabolic dysfunction-associated steatohepatitis (MASH, formerly NASH) among patients treated with GLP-1 receptor agonists

The pyridoxine component is relatively stable and does not impose additional storage challenges beyond what tirzepatide already requires

One of the reasons that vitamin B12 deficiencies are so common is that the symptoms are so broad and varied that it can be easily overlooked or mistaken for something else

By adhering to these storage recommendations, the medication will remain effective up until its beyond-use date, ensuring that patients receive the full therapeutic benefit from each dose