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Since the -2 subcluster is composed of cells exhibiting transcriptional signs of stress and the proportion of this subcluster was decreased upon liraglutide treatment, these data suggest that liraglutide-induced expression of XBP1 in the -1, -3, and -4 subclusters is a reflection of its protective action

J.Rodriguez-MartinA.TorresE.et al (2024)

Before starting Wegovy , inform your healthcare provider if you have: History of pancreatitis or gallbladder disease Pre-existing gastrointestinal conditions including inflammatory bowel disease or diverticular disease Severe gastrointestinal disease If you are pregnant, breastfeeding, or planning pregnancy (Wegovy must be stopped at least 2 months before planned conception) Regular follow-up with your prescribing clinician is essential to monitor treatment response, manage side effects, and ensure the medication remains appropriate for your individual circumstances

Park, J.H