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Contrary to the previous studies which compared BDNF level in the FM patients with the healthy subjects without pain, we chose the non-FM group from patients with NP to elucidate the role of serum BDNF more clearly in the different pain types

reduction in melanin levels alters the energy supply of cells in disease, which results in a lack of energy to sustain immune system defenses and remove the plaques seen in neurodegenerative diseases

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If the powder doesnt dissolve immediately with gentle swirling, refrigerating the vial for 15 to 30 minutes and then swirling again is a far safer approach