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Functional enrichment (GO/KEGG) and Gene Set Enrichment Analysis (GSEA) revealed that GGCT knocking down significantly impacted pathways related to the cell cycle, oxidative stress, cell proliferation, and cell death in both cancers (Fig

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Nevertheless, the contributory role of the TJ protein in mucosal barrier properties and pathobiology remains undeniable, but discerning their separate roles in barrier deregulation and epithelial morphogenesis appears to be a truly difficult task, at least given current technologies and model systems