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High SAH With Normal Homocysteine A normal homocysteine result does not rule out impaired methylation or elevated SAH

They include various free radicals and reactive molecules formed from molecular oxygen and nitrogen, including superoxide anion radical (O ), hydroxyl radical (OH ), hydrogen peroxide (H 2 O 2 ), singlet oxygen ( 1 O 2 ), nitric oxide (NO), and peroxynitrite (ONOO ) [28]

Environmental exposures such as UV radiation, pollution, and oxidative stress can trigger inflammatory pathways that accelerate visible aging

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