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10.1006/gyno.1994.1055 Gynecol

Neuroprotective effect of the Nrf2/ARE/miRNA145-5p signaling pathway in the early phase of spinal cord injury

Under conditions of chronic stress and inflammation, tryptophan is preferentially converted into quinolinic acid, a neurotoxin that overactivates N-methyl-D-aspartate (NMDA) receptors, leading to excitotoxicity and neuronal death [256]