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This means that the dosing question is not just "how much" but "for how long." A researcher who reaches their goal weight at month 8 needs to consider whether to continue at a maintenance dose, reduce to a lower maintenance level, or taper off with the understanding that some regain is likely

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In the intermediate stage, visual abnormalities may begin to appear, with some patients remaining asymptomatic while others show signs of blurry and distorted vision [21, 22]