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Thus, although an important point to keep attention to, data so far does not indicate that cardiovascular complications are a major cause for concern at the moment (gastrointestinal problems being by far the larger problem experienced by people on GLP1R agonists )

To contextualise that number: the landmark STEP 1 trial of semaglutide 2.4 mg showed a mean weight loss of approximately 14.9%, and the SURMOUNT-1 trial of tirzepatide reached 20.9% at its highest dose [2, 3]

An independent provider reviews eligibility and may prescribe medication