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vanno evitati i farmaci che inibiscono anche il trasportatore OATP1B, come il ritonavir

Overlapping binding sites of GLP-1 and Fab 3F52 The -helix of the GLP-1R ECD is a critical part of the GLP-1 binding site as shown previously by x-ray crystallography and it is also the primary binding site of Fab 3F52 as shown in this study 31

This not only helps control blood sugar levels but also prevents excessive storage of glucose as fat, thereby promoting weight loss

Alcohol is not formally contraindicated with semaglutide or tirzepatide, but clinical guidance advises caution because both affect the stomach, blood sugar, and hydration through overlapping pathways