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prescribed semaglutide who did not have a diagnosis of type 2 diabetes rapidly increased from 11.4% in 2020 to 41.7% in 2023 [Figure 2]

These medications slow gastric emptying and reduce appetite, which can inadvertently decrease fluid intake while increasing the risk of dehydration through gastrointestinal symptoms like nausea, vomiting, and diarrhea

Meanwhile these agents have the potential to reduce major adverse cardiovascular events (MACE) in patient with T2DM as a drug class, individual drugs have different potency and effects they need tailored approach to align with patient treatment goals rather than generalized use (117)

2%) were infrequent [11]