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If these measures do not work, an over-the-counter osmotic laxative like polyethylene glycol (MiraLAX) can be used daily as needed

Mounjaro (tirzepatide) is a prescription medication licensed by the MHRA for the treatment of type 2 diabetes mellitus and for weight management in adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbidity

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However, not everyone converts synthetic forms efficiently, particularly those with higher metabolic stress, liver strain, or certain genetic variations including the MTHFR mutation