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Administration of DSS in drinking water also resulted in the induction of a reproducible pro-inflammatory response, limited to the colon and characterized by lesions, loss of crypts, and infiltration of granulocytes, similar to PGN administration (Okayasu et al

"Once-Weekly Semaglutide in Adults with Overweight or Obesity"

These new trials (FLOW [29], SOUL [49], SELECT[68]) will be informative about additional patient groups that may benefit from GLP1-RA for kidney and heart protection