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Description

Administration: SubQ injections are most common for ease and convenience, though intramuscular (IM) is also used

In some embodiments, the otic formulation or composition comprises between about 0.01% to about 5% by weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof

41589_2021_915_MOESM20_ESM.mpeg Supplementary Video 18 Representative movie for 100 ns MD simulation of GPX4 K48R with the camera zoomed in for a close-up of the active site