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Additionally, markers of insulin sensitivity such as fasting insulin, fasting glucose, and fasting glucose/insulin ratio improved significantly with NAC but not with metformin

13 , 14 GSH as a regulator of innate immunity Anti-inflammatory role of GSH in lung diseases The idea that GSH may play an anti-inflammatory role became popular in the 1990s with a study by Schreck et al 15 showing that antioxidants inhibit, whereas ROS activate, the transcription factor NF-B that commands the transcription of several inflammatory genes, 16 a role that has been confirmed in the lung