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-catenin released from cell adhesions is also a pivotal signalling molecule driving various cellular responses (Valenta et al, 2012)

If, in the future, allogeneic therapies are scaled and a manufacturer makes payments to non-purchasing third parties for donor search, evaluation and cell procurement services, such payments may qualify as BFSFs and be excluded from ASP when they satisfy the four-part test at 414.802

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