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The gpoA transcripts, as well as tpxD and ahpD , which encode the TpxD thiol peroxidase and the AhpD alkylhydroperoxidase, respectively, were upregulated when pneumococci were exposed to H 2 O 2

Veldhuis JD, Keenan DM, Bailey JN, et al

Therefore, regulating tumour progression hinges on maintaining ROS below the critical threshold that supports oncogene dependence [23], on the basis of which targeted regulation of SOD activity is regarded as a potential strategy in cancer treatment [24]