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Abstract Aim: This study investigated the effects of semaglutide combined with metformin on body weight, glucose and lipid metabolism, sex hormone levels, menstrual cyclicity, and psychological parameters of women living with polycystic ovary syndrome (PCOS)-related infertility and overweight/obesity

Acknowledgments The main figures were assembled using BioRender ( The authors would like to acknowledge the support provided from their parent institution

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Los GLP-1RA, tomados diaria o semanalmente, reproducen el efecto de las hormonas GLP-1 del propio organismo, unindose a receptores especficos del cerebro y desencadenando secrecin de insulina en el pncreas