Mol Ther 32(9):31283144 Yao CC, Sun RM, Yang Y, Zhou HY, Meng ZW, Chi R, Xia LL, Ji P, Chen YY, Zhang GQ, Sun HP, Lu S, Yang C, Wang Y (2023) Accumulation of branched-chain amino acids reprograms glucose metabolism in CD8(+) T cells with enhanced effector function and anti-tumor response
Providing support for a causal link between a negative energy state and increased Parasutterella abundance, a rat model of obesity, which showed similar Parasutterella relative abundances in animals maintained on HFD and those maintained on normal chow but exhibited a treatment-induced increase in Parasutterella relative abundance, displayed a negative correlation between Parasutterella and body weight 82
Olaparib for metastatic breast cancer in patients with a germline BRCA mutation
Given the prior evidence for lower GSH levels in patients with MDD, our hypothesis is that glutathione levels may be lower in patients compared to healthy controls and that these differences may be brain-region specific
