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Otolaryngology Head and Neck Surgery 129 (3), S1S32 (2003)

doi:10.1002/hep.28270 [PubMed][CrossRef] Qu X, Donnelly R

They include brinzolamide (Azopt), dorzolamide HCl (Trusopt), and acetazolamide (Diamox

The role of R-2-HG as an oncometabolite has been implicated in epigenetic modifications through the inhibition of -KG-dependent dioxygenases and demethylases, which has been assumed to be a driver of tumorigenesis 117,118