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In mouse models of highfat dietinduced liver steatosis, it significantly inhibits hepatic NNMT activity, reduces NAM methylation, increases NAD+ and SAM levels, enhances mitochondrial fatty acid oxidation, reduces hepatic triglyceride and lipid accumulation, lowers lipotoxicity markers (e.g., malondialdehyde, transaminases), improves hepatocellular injury, and reverses steatosis
The Basic Properties of B12 and Uses in Health Vitamin B12, also known as cobalamin, is a water-soluble vitamin essential for nerve function, red blood cell production, and DNA synthesis
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