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The successful induction of RAI uptake (decreased thyroglobulin levels and decreased in tumor size) after treatment with rosiglitazone was showed in two studies performed in metastatic DTC patients (Elias and Lizotte, 2006

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RGC was reported in 17 (19%) of the GLP-1RA users as compared to 5 (5%) of the non-users, with an associated adjusted odds ratio (OR) increased by almost 6-fold (5.8 with 95% confidence interval [95% CI]: 1.719.3, P = 0.004)

Why Researchers Study Multi-Receptor Pharmacology Investigating molecules that engage several receptors is a way to probe fundamental questions in molecular biology and experimental pharmacology : Structurefunction relationships