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Prx3 is mainly restricted to mitochondria [52] , but is also found at the plasma membrane [53] , whereas Prx4 is found in the cytosol, the endoplasmic reticulum and as secreted protein [54]

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Muscle regeneration timing, satellite-cell dynamics, splicing regulation, and IGFBP profiles all differ across species and across ages, [19] and effects observed in a young rodent or a cultured cell line do not transfer automatically to human physiology

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