is fatigue a side effect of tirzepatide 20 Possible Effects Long-Term to Be Aware Tirzepatide Dosing - A Patient

Gastrointestinal symptoms are the most frequent side effects, affecting approximately 40% of patients during the initial titration phase

Together, these actions: Increase insulin release only when blood glucose is elevated Reduce excess glucose production by the liver Slow stomach emptying, limiting post-meal glucose spikes Act on appetite centres in the brain, increasing fullness and reducing hunger Because insulin release is glucose-dependent, Mounjaro on its own has a low risk of causing hypoglycaemia (low blood sugar), unless combined with insulin or sulfonylurea medications

They also slow gastric emptying so food moves slower through the stomach

It does not constitute medical advice