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1 2 3 4 Journal of Antimicrobial Chemotherapy

Eur Rev Med Pharmacol Sci (2017) 21(9):226873

Upon infection, this pro-viral state was consolidated: upregulated genes were enriched in pathways that hijack host functions, such as the G2/M phase transition of the cell cycle ( Reprogramming of transcription factor networks is the central hub regulating bipolarized host responses The profound coordinated changes in cellular function strongly suggested that the core operating system of the cellstheir TF networkshad been fundamentally rewired