The good news is these medications, semaglutide, the active ingredient in Ozempic and Wegovy, or tirzepatide, the active ingredient in Mounjaro, are part of a class of medications, GLP-1 receptor agonists, that have been around for over 20 years so we know the side effects, mostly gastrointestinal in nature (nausea, vomiting, constipation and diarrhea)
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TABLE 1 Mediators and activities