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At the end of the experimental protocol, the weight, blood glucose, insulin, triglyceride, and resistin levels of the HFD SEMA group were similar to those of the ND SAL control group

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Enrichment of TGF1 signaling pathways in mesenchymal stem cell-derived EV39-treated human preterm intestinal epithelial models To elucidate the molecular mechanisms underlying EV39-mediated maturation in premature intestinal organoids, we performed gene set enrichment analysis (GSEA), identifying TGF signaling as the most significantly enriched pathway in EV39-treated organoids (Supplementary Fig