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Instead, treatments are designed to: Address hyperpigmentation and patchy tone Improve texture, clarity and radiance Treat melasma, sun damage and acne marks Support long-term skin function and barrier health For a medically grounded overview of pigmentation and how it is commonly approached in dermatology, you can refer to trusted international resources such as the Cleveland Clinics guide on hyperpigmentation

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Animal studies have shown that when beta-3 adrenergic receptors were genetically removed, chronic AOD-9604 treatment produced no changes in weight or lipolysis, confirming the importance of this pathway

Gastrointestinal effects Nausea is the most common side effect, affecting roughly 41% of participants in the REDEFINE 1 trial