Although high doses of B12 are generally considered safe due to its water-soluble nature, most individuals can obtain sufficient B12 through a balanced diet that includes foods like meat, eggs, and fortified cereals
The selection of a three-times-weekly administration schedule accounted for preventing adverse effects of daily anesthesia, and potential localized irritation and toxicity within the nasal mucosa [41, 47]
As for Polyphenol Booster, it contains: Pomegranate extract (375mg) , shown in a 2022 study to increase short-chain fatty acids and regulate GLP-1 secretion at 375mg doses,32 while a 2025 study found that pomegranate in general can help proliferate beneficial bacteria, including Akkermansia 33 Grape seed extract (275mg) , which produces a significant prebiotic effect on Akkermansia , as in a 2021 study that used 200mg doses34 Green tea extract (225mg) , which also favors Akkermansia proliferation,35 potentially at doses as low as around 50mg in a 150lb human (as suggested by mouse studies)36 All very well-dosed to support Pendulums probiotic supplements
The chronic and evolving neurological consequences of traumatic brain injury