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Mitochondrial GR is essential for: Protecting the electron transport chain components from oxidative damage Maintaining mitochondrial DNA integrity against oxidative lesions Supporting ATP production by preserving mitochondrial membrane potential Preventing mitochondrial-initiated apoptosis triggered by excessive oxidative stress Facilitating mitochondrial glutathione transport and utilization The mitochondrial glutathione system is particularly critical in neurons and other cells with high energy demands, where mitochondrial dysfunction can have catastrophic consequences

Effects of acute and long-term administration of escitalopram and citalopram on serotonin neurotransmission: an in vivo electrophysiological study in rat brain

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Because muGIPR-Ab is long-acting, the order of pretreatments could not be counterbalanced