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In the hours before bedtime, some people with diabetes avoid the lifestyle variables that can cause hypoglycemia during sleep, such as carbohydrate-heavy meals (and the large doses of rapid-acting insulin that they require), alcohol, and exercise

This is one of the reasons these medications are associated with high rate of nausea and even vomiting. Patients who are on these medications have higher rate of excessive food residual in their stomachs despite going through the usual fasting period prior to procedures or surgeries, Rezaie explained

Holen, K., Saltz, L

These medications work best as long-term treatments