Soula M, Weber RA, Zilka O, Alwaseem H, La K, Yen F, Molina H, Garcia-Bermudez J et al (2020) Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers
The BH 4 /CoQ 10 system is comprised of two components, namely the ferroptosis suppressor protein 1 (FSP1)/CoQ 10 axis and the guanosine triphosphate cyclohydrolase 1 (GCH1)/BH 4 axis, and both pathways have been shown to inhibit ferroptosis independent of the xCT/GPX4 system [37]
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