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24 They are prescribed for type 2 diabetes mellitus (T2DM) and obesity, for which they currently have approval from the United States (US) Food and Drug Administration (FDA)

- Stop smoking, as it reduces antioxidant levels

Alternatively, it may be directly reduced by TRXR to H2Se, which serves as substrate for the utilization and excretion of Se and the biosynthesis of SeCys [16, 17]