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For instance, the administration of GLP-1 nanomedicine resulted in a decrease in IL-1, a pro-inflammatory cytokine, and a marked improvement of the architecture of the intestinal epithelium in a colitis model [223]

GLP-1 enhanced acetylcholine-induced forearm blood flow but had no effect on blood flow induced by sodium nitro-prusside in healthy human subjects [61]

Adherence and real-world outcomes will determine whether payers sustain coverage or retreat further Long-term safety: The newer indications (e.g., Alzheimers, liver disease) mean older populations, comorbidities, polypharmacy

DelParigi A, Tschop M, Heiman ML, et al