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524 Generalized myasthenia gravis (gMG) Generalized myasthenia gravis (gMG) is a disorder of neuromuscular junction transmission caused by the destruction of the postsynaptic membrane of skeletal muscle by autoantibodies at the neuromuscular junction

Oral lipotropics are better tolerated initially but require consistent daily dosing over 812 weeks to achieve comparable metabolic effects, whereas injections produce measurable changes in hepatic fat export and methylation status within 23 weeks

Screening recommendations target adults with risk factors including overweight, family history, age over 40, and ethnicity with higher diabetes prevalence

While human trials are still underway, early results are promising, with some patients reporting reduced pain and improved mobility after intra-articular GHK-Cu injections