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Approximately 20% of patients could have evidence of cirrhosis, which was defined as liver-biopsy results showing a Metavir fibrosis score of 4 or an Ishak score of 5 or more, a FibroTest score of more than 0.75 and a ratio of aspartate aminotransferase to platelets of more than 2, or a FibroScan reading of more than 12.5 kPa

239 The lack of a characterized H 2 O 2 -specific CsoR-family sensor prevents a detailed side-by-side evaluation of the oxidant specificity of a bona fide RSS and ROS sensor, limiting our understanding of inducer specificity in this structural class of repressors

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