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The circadian rhythm governs the sleep-wake cycle, sleep neurons control the transition between wakefulness and sleep, and neurochemical regulation involves various nervous systems and chemical substances ( Sleep is fundamental in regulating the hypothalamic-pituitary-adrenal axis, which is involved in growth hormone (GH) release

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Delta Sleep-Inducing Peptide (DSIP) is a naturally occurring peptide first identified in the hypothalamus and has since become a focal point in research on circadian rhythm, hormonal balance, and neuroprotection