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Crucifers blocking iodine and exacerbating iodine deficiency was a major concern in the 1950s, as then, the primary reason for hypothyroidism was due to iodine deficiency

transient impairment of glucose tolerance is possible, particularly in individuals with pre-existing insulin resistance Injection site reactions: Mild and typically localised Contraindications include active malignancy (GH-IGF-1 signalling can promote tumour growth), pituitary-dependent conditions, pregnancy, and active diabetic retinopathy

The research, published in JAMA Psychiatry, provides reassurance that use of GLP1-RAs, such as semaglutide, are not associated with any increased risk of psychiatric adverse events or worsening of depressive symptoms