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Collectively, it indicates that HDAC4-p53 interaction functions as an intriguing target due to the inhibition of p53 caused by HDAC4-mediated deacetylation

From these findings and the fact that glutathione is essential for lymphocyte proliferation and immune responses, , we hypothesized that abundant cystine/cysteine in the kidneys forms a unique metabolic microenvironment that supports ectopic lymphocyte proliferation, leading to the formation of TLS

Figure 6 shows a clear uptake of labeled PLGA nanocarriers with AuNCs with bright red photoluminescence at loading capacity of 0.79 weight % (gold/polymer, determined using ICP-MS analysis)