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On the basis of the gold score, it is noted that most of the carcinogens/toxins bind almost equally with both wild and mutant GSTP1, except for gallotanic acid, a derivative of RAN, showed better binding with GSTP1 GG-genotype (Table 4), whereas N-nitrosonornicotine (NNN), a derivative of tobacco, showed better binding with GSTP1 AA-genotype (Table S6)

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This review provides an overview of human in vitro models and their achievements in unravelling the Fabry disease pathomechanism as well as in elucidating current and future treatment strategies

Other Ingredients:Rice Powder, Microcrystalline Cellulose, Vegetable Capsule (Hypromellose)