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Therefore, what have been of particular interest are the effects of GLP-1 on these clearly defined pathways that promote kidney injury, such as oxidative stress, fibrosis via enhanced prosclerotic factor action, and inflammation

Their multifaceted mechanisms, including glucose-dependent insulin secretion, appetite regulation and cardio-renal protection, allow for therapeutic adaptation across patient subgroups, such as those with obesity, established cardiovascular disease or varying stages of DKD [62,63,64]

Florida passed legislation annually from 2022-2025 implementing a pilot program through the state employee health plan, which offers GLP-1 coverage and tracks participants clinical health outcomes

Ghrelin receptors in rat and human nodose ganglia: putative role in regulating CB-1 and MCH receptor abundance