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Mitochondrial dysfunction itself can be categorized into two types: the first type represents a mutation of a gene which is associated with the ATP-generating pathway, while the second one is related to various abnormalities such as genetic, biochemic or metabolic, that may weaken the ability of the mitochondria to produce ATP ( A central mechanism often implicated is the dysfunction of Electron Transport Chain (ETC), which plays a crucial role in ATP production

SeNPs offer several advantages over conventional Se compounds, such as sodium selenite or SeMet [107]

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