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We also downloaded AlphaFold-predicted structures for the conserved C-terminal region of SyeA for several distantly related Buchnera lineages ( Buchnera -Cc, Buchnera -Ua and Buchnera -Bp, corresponding to UniProt Q5EU88, G2LQ59 and Q89A26) and compared these to that for Buchnera -Ap to assess extent of structural similarity across Buchnera

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do Rosario, M

Specific class II HLA loci can encode major histocompatibility complex (MHC) molecules that may contain the shared epitope (SE) ( In addition, various studies have suggested that mucosal environmental exposures and/or mucosal dysbiosis play a causal role in the period of susceptibility to RA ( In this review, we summarize recent literature to help better understand the role of gut microbiome in RA, and to evaluate the therapeutic and preventative effects of probiotics in RA, providing a solid framework for future studies of optimizing the management of the health status of patients with RA