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BS has also shown to have an overall mortality benefit in severe obesity and has favorable effects on metabolic parameters and comorbidities such as hypertension, hyperlipidemia, metabolic syndrome, cardiovascular risk and glycemic control in diabetes

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134 , e175634 (2024)

Figure 1 2.1 The mechanism of ferroptosis 2.1.1 The GPX4/GSH signaling pathway in ferroptosis GSH is the primary antioxidant involved in intracellular antioxidant stress, participating in numerous essential cellular metabolic activities such as the removal of ROS, DNA and protein synthesis, and signal transduction