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We also calculated the greatest HbA1c reduction for each patient, which was used for a stratified analysis: patients were divided according to a few key baseline characteristics and the greatest HbA1c reduction was compared across strata to evaluate if any patient subgroup displayed greater glycaemic improvements

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Survodutide# Survodutide (BI 456906) is a dual agonist that activates both the GLP-1 receptor and the glucagon receptor (GCGR), with an activity ratio favoring glucagon receptor activation approximately 4-5 fold over GLP-1R

So those two, if they're present, we really want to work that up with an MRI