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These medications: reduce appetite lower inflammation improve liver fat improve metabolic markers reduce cardiovascular events (SELECT trial) They do not : build muscle increase VO max improve mitochondrial function replace strength training fix metabolic flexibility guarantee long-term weight maintenance 2

"While we acknowledge your response that an abrupt shortening of the enrollment period led to challenges and mistakes, your response is inadequate because, regardless of the length of the enrollment period, you are still responsible for ensuring that subjects meet protocol-specified eligibility criteria before you enroll them into the study," said FDA

It stimulates collagen and elastin production, enhancing skin elasticity and reducing visible signs of aging

Although the trial did not show a significant advantage in reducing cardiovascular events [6], or hospitalizations, it provided insights into liraglutides safety and tolerability in this patient population [6]