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The expression of pro-ferroptosis genes was also found to be downregulated in the epidermis of mutant mice, and the expression of ferroptosis-suppressing genes such as Gpx4 and Slc7a11 was upregulated

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Apolipoprotein A-I activates protein kinase C alpha signaling to phosphorylate and stabilize ATP binding cassette transporter A1 for the high density lipoprotein assembly