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In adipose models, reduced NNMT activity has been linked with smaller adipocyte size and diminished fat depots, suggesting a potential role for this inhibitor in fat mass modulation under research conditions

"Health Canada won't approve it as a drug, but it slips through as a compounded natural health product, where the federal safety check basically doesn't happen." Health Canada considers NHP compounding within a practitioner-patient relationship distinct from manufacturing and not subject to the same regulatory oversight

The choice of dose, frequency, and cycle length is a clinical decision and should be made with a licensed provider familiar with the published literature

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